Wednesday, July 04, 2007

Axtinib Phase II Study Shows Promise in Pancreatic Cancer

Pfizer's multi kinase VEGFR inhibitor axitinib has shown interesting results in Phase II study in Pancreatic cancer.
Interim results from a Phase II trial: axitinib + Gemzar median OS 6.9 months vs 5.6 months for single-agent Gemzar - a 26% reduction in the risk of death. In a subset of 94 patients with a good performance status, the combination reduced the risk of death by 33%

Word on the street is that axitinib is about to move into Phase III in pancreatic cancer - in 2H 2007